Improving the transparency, reproducibility, and trustworthiness of science
I am an associate professor of neuroscience at Karolinska Institutet, a researcher at Stockholm University. I am further affiliated to the METRICS center at Stanford University and I collaborate closely with the QUEST Center in Berlin where I was recently a visiting fellow. I am a national coordinator of domain specialists with the Swedish National Data Service, a role which entails promoting data sharing in science through education, advocacy, and providing resources. Since 2017 I teach a PhD course in open science and reproducible research at Karolinska Institutet. I am co-chair of the EOSC Association task force on researcher careers, recognition and credit, and a member of numerous committees and groups working on open science and research assessment.
Metascience
I work in metascience to assess and improve transparency and reproducibility of research using quantitative methods. Particular interests include multi-analyst designs, quality control and error checking, researchers’ incentives, and evidence synthesis.
Neuroscience
My research in neuroscience concerns mainly sleep, diurnal rhythms, and markers of inflammation. For many years I ran a research programme involving experimental studies of sleep deprivation using brain imaging. Currently I am working mainly on projects aiming to collect large amounts of existing data for secondary analysis. The discovery I feel most proud of is that interleukin-6, a signalling molecule of the immune system, does not increase in the blood of healthy humans at night, as previously thought; this disproves a role for interleukin-6 as a sleep regulatory substance mediated by the blood.
Psychiatry
Together with colleagues, I run projects to assess biomarkers in psychiatry and to develop better ways to predict interventions for patients.
In the media
- 2023-03-07: Debate article in the Swedish Medical Journal: Ofullständig rapportering av studier försämrar kunskapsläget (in Swedish)
- 2023-02-24: Interviewed in Weekendavisen about a study on infants’ screen time and cognitive development (in Danish)
- 2022-11-02: Feature by TranspariMed on the project to follow up Nordic clinical trials
- 2022-10-31: Interviewed in a feature in Nature about artificial intelligence tools in research
- 2022-10-19: Debate article in Curie: Dags att förnya hur forskning bedöms (in Swedish)
- 2022-05-03: Debate article in Svenska Dagbladet: Dags att överge traditionella tidskrifter. (in Swedish)